What makes up the highest percentage of an adult human's body weight?
Water makes up a significant fraction of the human body, both by weight and by volume. For the first few months of life, nearly three-fourths of your body weight is made up of water. However, that percentage starts to decline as you continue to age. While the average percentage of water in an adult’s human body is around 60%, the percentage can vary from roughly 45–75%. Both the brain and heart are composed of approximately 73% water, and the lungs are about 83% water. The skin contains 64% water, muscles and kidneys are 79%, and even your bones are made up of 31% water.
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