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Who was David Letterman's first and last guest on "Late Night with David Letterman"?
David Letterman ended his late-night career with the same guest he started with. When Late Night with David Letterman debuted on February 1, 1982, the first guest on the first show was Bill Murray. Murray went on to become one of Letterman's closest friends, guesting on his show's celebration of his 30th anniversary in late-night television, and on the shows finale which aired May 20, 2015. Through the years, Bill Murray was of Letterman's most recurring guests, appearing on Letterman’s show 44 times over the its 33 years run.
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